New AI Model “Squidiff” Predicts Cellular Responses to Accelerate Precision Medicine

November 10, 2025

New publication alert! The Azizi and Leong labs at Columbia University, in collaboration with the Zou group at Stanford University, have introduced Squidiff — a diffusion-based AI model designed to predict cellular responses to developmental and chemical cues, advancing the field of precision medicine.

Squidiff surpasses existing approaches by helping researchers uncover potential drug targets and gain deeper insight into disease mechanisms. The study is now published in Nature Methods.