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Her team successfully engineered a specially designed strain of probiotic E. coli that is safe for use in treating brain tumors. This innovative approach harnesses the bacteria’s ability to interact with the tumor environment, where the engineered microbes activate local immune cells in the brain. Their findings reveal that this immune activation plays a key role in the therapeutic effectiveness of the treatment, offering a promising new strategy for targeting tumors through precision microbial engineering.

New publication alert! The Azizi and Leong labs at Columbia University, in collaboration with the Zou group at Stanford University, have introduced Squidiff — a diffusion-based AI model designed to predict cellular responses to developmental and chemical cues, advancing the field of precision medicine.

At the 2022 annual meeting of the Society for Biomaterials in April, our doctoral student Shuting Sarah Cai gave a presentation titled "Non-viral Gene Editing in Mouse Brain Achieved by Focused Ultrasound via Systemic Delivery". Her impressive speech was awarded Best Oral Presentation by the Engineering Cells and Their Microenvironments special interest group of the SFB meeting. This is an amazing achievement. Congratulations to Sarah!